E4BP4 is an insulin-induced stabilizer of nuclear SREBP-1c and promotes SREBP-1c-mediated lipogenesis
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چکیده
منابع مشابه
mTORC1 activates SREBP-1c and uncouples lipogenesis from gluconeogenesis.
Correction for “mTORC1 activates SREBP-1c and uncouples lipogenesis from gluconeogenesis,” by Mathieu Laplante and David Sabatini, which appeared in issue 8, February 23, 2010, of Proc Natl Acad Sci USA (107:3281–3282; first published February 18, 2010; 10.1073/pnas.1000323107). The authors note that, on page 3281, left column, second paragraph, the fourth sentence is incorrect in part. “In add...
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Sterol-regulatory-element-binding protein 1c (SREBP-1c) is one member of the family of transcription factors that stimulate sterol and fatty-acid biosynthesis in animal cells. Human SREBP-1c, mapped to chromosome 17p11.2, is expressed in liver, intestine, skeletal muscle and adipocytes. A section of genomic sequence from a chromosome 17 library, thought to contain the SREBP-1c promoter, was clo...
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ژورنال
عنوان ژورنال: Journal of Lipid Research
سال: 2016
ISSN: 0022-2275
DOI: 10.1194/jlr.m067181